5 FACTS: Complex Regional Pain Syndrome (CRPS)

As doctors are learning more about the condition, they are realizing how many aspects of medicine play a role in its formation.  Its a complex disorder.  Many doctors avoid discussing it because they dont have a clear understanding of its causes.  But medicine is beginning to shed light on its cause.

complex regional pain syndrome

1) THREE TIMES MORE COMMON IN FEMALES

Complex Regional Pain Syndrome (CRPS) occurs 3x to 4x more commonly in females by most estimates, however doctors dont know why.  Also, interestingly, the risk for it increases with age for both men and women.  The increased risk in women suggests there is some type of endocrine influence (our hormones may predispose certain people to being at increased risk).

2) ITS CHARACTERIZED BY A COLLECTION OF SYMPTOMS

Complex Regional Pain Syndrome is diagnosed when there is a collection of common symptoms.  All of these symptoms dont have to be present, but usually a few of the following are observed: pain, swelling, muscle weakness, decreased joint motion, color changes (also called vasomotor instability), sweating, changes to the skin/hair/or nails.

3) USUALLY OCCURS AFTER AN INJURY (OR SURGERY) TO THE AFFECTED LIMB

A broken bone, or a sprain, crush injury or surgery usually precedes the injury.  Injuries to the upper extremity (like a distal radius fracture, see talk) are more commonly affected by CRPS, than lower extremity injuries (like an ankle sprain, see talk).  

4) PHYSICAL THERAPY IS AN EFFECTIVE TREATMENT

Physical therapy is aimed at regaining and maintaining range of motion and muscle strength.  Also, the affected limb can become desensitized to pain with frequent use.  However, physical therapy is often one side of a multi-sided approach to treatment.  Vitamin C, anti-inflammatory pain medication, and diphosphonates are also beneficial.

5) MOST CASES WILL RESOLVE WITH TIME

Recent studies have shown that CRPS treated with physical therapy and pain medication will resolve in almost 75% of patients.  Both men and women have an equal chance of getting better.